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Perinatal Mortality Tables


Congenital anomalies are an important contributor to perinatal mortality.  In EUROCAT the overall recorded rate of late fetal deaths/stillbirths with congenital anomaly is 0.47 per 1,000 births for 2004, and of deaths in the first week 0.46 per 1,000 births, for a total perinatal mortality rate associated with congenital anomaly of 0.93 per 1,000 births (Table 1).  The main congenital anomaly subgroups contributing to perinatal mortality are congenital heart disease (26% of perinatal deaths with anomaly), nervous system anomalies (21%), and chromosomal anomalies (25%) (Table 1).  Chromosomal anomalies and nervous system defects contribute more to stillbirths than to deaths during the first week, while congenital heart disease is almost equal in both categories (Table 1).

Perinatal mortality associated with congenital anomaly varies by country (Table 2).  The highest rates of perinatal mortality associated with congenital anomaly are recorded in Ireland (2.4 per 1,000) and Malta (2.6 per 1,000).  These are both countries where TOPFA is illegal, and thus the perinatal mortality rate includes affected fetuses with a lethal or high mortality anomaly which would, in other countries, have led to TOPFA and exlcusion from mortality statistics.


Table 1 - Perinatal Mortality Associated with Congenital Anomalies in EUROCAT Full Member registries Combined, 2004,* by Type of Anomaly

Table 2 - Fetal Death, Early Neonatal, Perinatal and Neonatal Mortality Associated with Congenital Anomalies per Country, 2004

Table 3 - Rate of Terminations of Pregnancy for Fetal Anomaly Following Prenatal Diagnosis (TOPFA) and Rates of Perinatal Deaths* per 1,000 Births by Country, 2004, EUROCAT Full Member Registries